What is Malegra?
Malegra is an oral medication that treats erectile dysfunction, and it can cause psychological trauma, stress, and even prostatitis. Malegra is not a hormone nor a way to induce excitement or aphrodisiac, and most patients can use it every day.
Mechanism of action
This drug aims to relax the smooth muscle and normalize the blood flow in the penis and hollow bodies. It is caus by sildenafil, which is the active ingredient in Malegra. That inhibits (suppresses) the enzyme phosphodiesterase 5—prevents hat standard vessel opening.
Malegra, in other words, increases the penile vessels and brings blood flow to the erectile organs of the male genitalia. The penis hardens and grows in size.
Sildenafil pills should take 40-60 minutes before the scheduled sexual act: the effect 4 and 6 hours. The effect duration can be adjusted to suit the particular needs of each individual.
The medicine can also be used to treat erectile dysfunction and pulmonary hypertension.
Malegra 100 mg also contains a variety of auxiliary substances. Microcrystalline cellulose is 313.162 mg, hydro calcium phosphate is 104.388 mg, and croscarmellose salt – 30 mg. Magnesium stearate is 12 mg.
Where is Malegra made?
Sunrise Remedies pvt. Produces malegra in India. Ltd. Ltd. The company is a specialist in the production of generic drugs, which is a common practice for other companies in the industry.
It is very different to develop drugs from making them. That requires a lot of financial and other resources and a large amount of research and development. That means that drug developers can charge much higher prices for their products. This is what happens with Viagra, sildenafil, and other brands. Malegra manufactured by an Indian non-developer company sells 10% less than the original cost. That explains why Malegra is so prevalent in online pharmacies.
The only difference between brand and generic sildenafil is price, name, and excipients. These ingredients give the pill its shape, color and hold the active ingredient in place. They have no pharmacodynamic or pharmacodynamic values, but they do not affect effectiveness. The company interested in manufacturing sildenafil must demonstrate in clinical trials that it has the same effect as the original drug to grant a manufacturing license. It is usually sufficient to prove that the generic drug has identical pharmacokinetics (i.e., it delivers the same amount of active substance into the bloodstream of patients) to get a license for manufacturing it.
Sunrise Remedies Pvt. Ltd. has approve the production of sildenafil in India under the name Malegra. That means that the drug’s safety and efficacy are comparable to Viagra in the U.S.
Malegra: How do you use it?
Start with 50 mg. This amount is enough to get the drug’s full effects in 80% of cases. It is best to take the medication with food and not alcohol. The impact and health of the user can influence the dose. A 100mg dose in 24 hours is recommende for people who desire occasional solid effects. To avoid side effects, it is best not to exceed this dosage. In prolong treatment or the presence of certain conditions, the minimum dose is best.
Malegra is very effective.
Numerous researches have been conducted around the world to evaluate sildenafil’s clinical efficacy in Malegra. We can see the results of 11 double placebo-controlled research studies that involved almost 3,000 patients with erectile disorder.
Within 12 weeks, 76% of men who received the drug and 22% who received a placebo experienced an improvement in erection. The percentage of men who successfully test for the sexual act in the first and second groups is 66% and 26%, respectively.
Different doses of sildenafil have different efficacy. They are 65% for 25mg, 74% for 50mg and 82% respectively for 100mg.
Malegra’s high effectiveness has been demonstrated for all ages. Malegra’s efficacy was high in older patients, 65 years and younger, with a 77.6% and 69%, respectively.
The results data can only be obtained if the instructions for their use are followed and there are no contraindications.
Sildenafil is the base of both generic and brand drugs that helps restore harmony in intimate relationships for millions worldwide. It is the most researched mechanism of action. Despite the fact that there are other drugs with a longer duration of effect, Sildenafil still holds its own today as “pill number one for men”. Since long, the name of this drug is synonymous with masculinity and sexuality.
Side effects of Malegra are rare and usually occur in less than 5 percent of cases. They can be temporary and disappear if the intake is changed or if the medication is switched to another PDE5 inhibitor. The table below shows the frequency of adverse effects associated with Malegra.
Malegra side effects on the eyes are very rare. Only 5% of men reported color recognition dysfunction. It is usually caused by the following risk factors: smoking, diabetes, hypertension and age over 50.
Also less common (less than 1%) are blurred vision, eye pain, photophobia and red eyes (sclera), variations in the recognition luminosity, conjunctivitis, bloody eye tissues, dysfunctional lacrimal system, dryness sensation in the eyes.
Malegra side effects are rare and decrease in frequency with continued administration.
Malegra administration has no adverse effect on the cardiovascular system. It has the opposite effect. It improves the function of the endothelial vessel functional status, which is critical for the pathogenesis and progression of many cardiovascular diseases.
To avoid side effects from misuse or overdose, make sure you read the instructions and adhere to the label.
Avoid using this product in conjunction with alcohol. A combination effect of vasoactive agents may cause a sudden and severe drop in blood pressure.
Avoid mixing grapefruit juice and grapefruit juice. Concomitant administration can lead to delayed clearance and toxicity.
It is not possible to provide clinical data regarding pregnancy. This drug is not recommend for use in pregnant women, minors, or female population.
Patients of all ages and with different health conditions can use Malegra. People with many comorbidities, such as diabetes, can tolerate the drug well. Malegra is not recommend for people with certain conditions. We have listed the most common, but this is not a complete list. Your doctor or pharmacist should be aware of all conditions that you may have or are currently experiencing.
- Stroke history within the last 6 months
- heart failure
- Peyronie’s disease, a hereditary penile defect called Peyronie’s Disease
- Retinitis pigmentosa is a hereditary condition that affects the eyes.
- NAION (ocular neuropathy)
- Multiple myeloma
- Sickle cell disease
- Renal failure
- Hepatic failure
- duodenum ulcer
- stomach ulcer
- Blood pressure irregularities (excessively low or high blood pressure)
- Sensitivity to PDE5 inhibitors